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I Am a Researcher

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Stephanie Ugochukwu

Major(s): Molecular and Cell Biology

College: Warren College

UC San Diego graduation year: 2025

URH Research Programs: 

  • STARTneuro (Summer 2023 - Present)
  • Genentech Scholars Program (Summer 2024)
What are you researching (or did you do in the past)? 

I'm working in the Augustine lab to perform a comprehensive dissection of the superior cervical ganglia (SCG) and investigate its neuroendocrine role in regulating cardiac physiology in disease and health. We have preliminary data that shows that neurons in the SCG project to the heart and glands such as the thyroid and pineal gland. This project entails inducing heart failure in a mouse model by performing transverse aortic constriction (TAC) surgery and then probing the function of SCG neurons to study their role in heart disease development while modulating hormone secretion in glands. Through ECG, ultrasonography, and immunohistochemistry analysis, we'll witness the impact of the SCG neurons and hormone dysfunction on the development of heart failure. 

Why and how did you decide to get involved in undergraduate research? 

I first got involved in research while attending Solano Community College. I worked under Professor Michelle Smith on the BUZZ Project organized by the College of the Canyons. Our goal was to combat the decline of California's native bee populations by studying their presence on community college campuses. I initially joined because I enjoyed Professor Michelle's ecology course and wanted to apply my understanding in a field research setting, however, the experience opened my eyes to my desire to pursue research as a career. I knew I wanted to study the brain-body connection, so when I transferred to UCSD I applied to STARTneuro, a program dedicated to supporting transfer students interested in neuroscience research.

What has been the most exciting/interesting thing you've discovered through this research?

The most exciting thing I've learned from my research is the possibility for the SCG to serve as a conduit for treating cardiovascular disease. I enjoy being able to contribute toward expanding our perspective on the illness and creating the foundation necessary for future scientists to develop neuromodulation techniques that could provide a less costly but still effective route for treatment and prevention. 

thumbnail_IMG_7250.jpgWhat did you gain from this program/experience?

My confidence has grown a lot since I started conducting research at UCSD. I have a great mentorship network because of the Augustine lab, STARTneuro, and BUMMP. Having people who believe in me and encourage me to strive for more has made me grow as a researcher in so many ways. I feel more confident in my ability to carry out a research project independently, learn new laboratory techniques, problem solve, and write proposals and applications for opportunities I'm interested in. 

What advice would you give to students starting research?

I think the cool thing about UCSD is that there is a strong community for those interested in research careers. I believe the mentorship I've received while conducting research has been one of the most valuable things I've gained from the experience. I would encourage anyone interested in research to join programs that provide support to undergraduate researchers. A great mentor can offer you so much advice and uplift you when you need it.

What are your future goals?

This fall I plan to spend time working on applications for neuroscience/biology PhD and post-baccalaureate programs. As of now, I'm interested in going into translational research, however I'm open to exploring other fields while I pursue a PhD. 

 

Pictures

  • Stephanie Ugochukwu Profile
  • Stephanie Ugochukwu conducting her research