I Am a Researcher
Liana Melikian
Major(s): Human Biology and Public Health
College: Thurgood Marshall College
UC San Diego graduation year: 2024
URH Research Programs:
Which URH Programs have you been a part of?
Dr. Maryam Ahmadian Summer Research Fellowship Program (Summer 2024)
What are you researching?
I have been exploring glycogen not just as an energy reservoir in the liver, but also as a signaling molecule that regulates energy homeostasis in hepatic glucose metabolism. My focus has been on how glycogen levels influence gluconeogenic gene expression in hepatocytes.
Why and how did you decide to get involved in undergraduate research?
I've always been fascinated by the molecular mechanisms underlying metabolic diseases like obesity and diabetes. When I discovered the Saltiel Lab through a campus club, I knew it was the ideal opportunity to apply my passion and knowledge in these areas. By contributing to the scientific literature, I aim to advance our understanding of these diseases in order to benefit both the academic and medical communities.
What has been the most exciting/interesting thing you've discovered through your research?
Uncovering the specific mechanism by which glycogen regulates gluconeogenesis was particularly exciting. Demonstrating an effect is one challenge, but proving the underlying process is another. By elucidating this mechanism, we pave the way for developing novel therapeutics for metabolic diseases.
What did you gain from this program/experience?
I’ve gained numerous lab-related technical skills that have helped me to confidently plan and design my own experiments. Additionally, I’ve improved my ability to present scientific research, enhanced my networking skills, and become a more effective problem solver. Most importantly, my research experience has inspired me to pursue graduate school in biology.
What advice would you give to students starting research?
I strongly recommend discussing your mentor’s experiments, their results, and how they align with the overall scientific hypothesis to deepen your understanding of the research. Don’t hesitate to ask questions—open communication and a solid mentor-mentee relationship are crucial for becoming a successful researcher.
Pictures
- Liana Melikian profile picture